EPIDEMIOLOGICAL FEATURES OF ESOPHAGEAL MUCOSAL LESION ON DIFFERENT SEX IN HIGH RISK POPULATION OF ESOPHAGEAL CANCER

Endoscopic and pathologic examinations were conducted in a randomly chosen different sex population who were 35 years or older in a high risk area of esophageal cancer,Huai’an County, jiangsu Province. The results showed that the prevalence of chronic esophagitis was the highest(24.88─30.25%)among all mucosal lesions,and the second was the rate of proliferative abnormalities of the esophageal epithelium( 4.39─3.20%).It was showed that the positive rate was sifnificantly increased in both sex with the age.X2 value were from 3.988─9.119.P is less than 0.05 or01.Esophageal mucosal lesions changed from mild to severe with a decline in transition rate. All the rated were higher in male than that in female except chronic esophagitis.The transition rates were also significantly higher in males.The stusy suggested that esophageal precancerous lesions are related to malignant changes which is not a short period of time. The progression from chronic esophagitis to cancer may take an average of 23─26 years.This make it possible to carry out primary and secondary prevenrion of esophageal cancer in the high risk popuiation.