Clinical Study of Diagnosis and Treatment in Solid-pseudopapillary Tumor of Pancreas

Objective To summarize the experience of diagnosis and treatment in solid-pseudopapillary tumor of pancreas(SPT).Methods A retrospective clinical analysis was made on 18 cases of solid-pseudopapillary tumors of the pancreas admitted from June 2000 to February 2008.Results The tumors of 4 cases were located in the pancreatic head,the tumors of 2 cases was in the neck of pancreas and 12 tu-mors were in the body and tail of pancreas,without specific clinical manifestations.Solid and solid-cysticmasses of low echo were found in pancreas transonic examinations.masses of low density in pancreas was found on CT scan,while irregular enhancement appeared in the cir-cumference of all tumors in enhanced CT scan sequences.Tumor markers in patients'serum were all negative.3 Patients underwent distal pancreatectomy.Simple resection of tumor was performed in 6 cases.9 patients underwent distal pancreatectomy and spleen resection.18 pa-tients were followed up for the average time of 11.2 months.No evidence of relapses and metastasis in these cases was found.Conclusion Huge pancreatic masses of pancreas in young females should suggest the diagnosis of solid-pseudopapillary tumors.Aggressive surgical thera-py can achieve good prognosis in these patients.