Progress in pathogenesy of irritable bowel syndrome

The pathogenesis of irritable bowel syndrome(IBS) is complex and still incompletely known.The current consensus view is that IBS is involvedin abnormal gastrointestinal motility and secretion,visceral hypersensitivity,intestinal infection,psychosocial factors,neurological-immune-endocrine axis and other genetic mechanisms.This article is an review about of the advance in pathogenesis of IBS in recent years.