The Clinical Significance of Plasma D-dimer Detection in the Diagnosis of Excluding Pulmonary Embolism

Objective The aim of this study is to evaluate the value of the plasma D-dimer detection in the diagnosis of excluding pulmonary embolism.Methods D-dimer levels were determined by enzyme-linked immunoabsorbent assay (ELISA) in patient with suspicion of pulmonary embolism,and carries on for half year to those patients to make a follow-up visit to see whether they have the symptom of pulmonary embolism or deep phlebothrombosis.Results Of all the 102 patients included,were detected,D-dimer levels were below 500 μg/L in 42(41.1%)patients,D-dimer levels were above 500 μg/L in 60 patients,12 of them were proved were diagnosis of pulmonary embolis by pulmonary angiography V/Q.Lung scan Sensitivity and negative predictive values of D-dimer detection were 100%.Conclusion D-dimer detection is easy to work out and do not need complex equipment,it could be the first test of excluding pulmonary embolism,and is easyto spread in clinical diagnose.