A review of the influences of microplastics on toxicity and transgenerational effects of pharmaceutical and personal care products in aquatic environment

PPCPs (pharmaceutical and personal care products) and microplastics (MPs) are two types of emerging pollutants that are ubiquitous and widely concerned in the environment. Both of them can accumulate in fish or aquatic invertebrates and transfer to offspring, thereby producing toxic effects on both parents and offspring, in which the characteristics of MPs also enable them to adsorb PPCPs thus producing carrier effects. In this study, we have conducted a comprehensive review of MPs and PPCPs and found that MPs can act as a carrier of PPCPs to influence the bioaccumulation of PPCPs. MPs and PPCPs have toxicity and transgenerational effects on both fish and aquatic invertebrates in many aspects, and MPs can also affect the toxicity and transgenerational effects of PPCPs due to their carrier effects. This paper revealed that MPs may have an important impact on the bioavailability of PPCPs and the interaction between MPs and PPCPs is a hot topic in future research. This study also puts forward the shortcomings of the current research and related suggestions, and relevant research should be carried out as soon as possible to provide the basis for the prevention and treatment of fresh water.