自愈水凝胶
再生医学
组织工程
背景(考古学)
纳米技术
天然聚合物
材料科学
化学
聚合物
生物医学工程
生物化学
细胞
生物
高分子化学
工程类
有机化学
古生物学
作者
Marta Calvo Catoira,Luca Fusaro,Dalila Di Francesco,Martina Ramella,Francesca Boccafoschi
标识
DOI:10.1007/s10856-019-6318-7
摘要
Hydrogels from different materials can be used in biomedical field as an innovative approach in regenerative medicine. Depending on the origin source, hydrogels can be synthetized through chemical and physical methods. Hydrogel can be characterized through several physical parameters, such as size, elastic modulus, swelling and degradation rate. Lately, research is focused on hydrogels derived from biologic materials. These hydrogels can be derived from protein polymers, such as collage, elastin, and polysaccharide polymers like glycosaminoglycans or alginate among others. Introduction of decellularized tissues into hydrogels synthesis displays several advantages compared to natural or synthetic based hydrogels. Preservation of natural molecules such as growth factors, glycans, bioactive cryptic peptides and natural proteins can promote cell growth, function, differentiation, angiogenesis, anti-angiogenesis, antimicrobial effects, and chemotactic effects. Versatility of hydrogels make possible multiple applications and combinations with several molecules on order to obtain the adequate characteristic for each scope. In this context, a lot of molecules such as cross link agents, drugs, grow factors or cells can be used. This review focuses on the recent progress of hydrogels synthesis and applications in order to classify the most recent and relevant matters in biomedical field.
科研通智能强力驱动
Strongly Powered by AbleSci AI