黑色素瘤
聚ADP核糖聚合酶
PARP1
癌症研究
医学
黑色素瘤诊断
荧光团
病理
化学
聚合酶
荧光
酶
生物化学
量子力学
物理
作者
Aditi Sahu,Aundree Hermawan,Melissa Gill,Ucalene Harris,Thomas Reiner,Ashfaq Marghoob,M. Cecelia Lezcano,Anthony Rossi,Allan C. Halpern,Klaus J. Busam,Chih‐Shan Jason Chen,Manu Jain,Milind Rajadhyaksha
标识
DOI:10.1364/translational.2022.tw3b.4
摘要
Towards early melanoma diagnosis using a poly-ADP-ribose polymerase1 (PARP1)-targeted fluorophore, we evaluated PARP1 expression in benign and malignant lesions. Higher PARP1 expression in malignant lesions confirms clinical utility of the approach.
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