Albinism is an autosomal recessive genetic disorder characterised by hypopigmentation of the eyes, skin and hair. It has been linked to other conditions such as Hermansky-Pudlak Syndrome (HPS). HPS is relevant to the dental profession because of the platelet disorder associated with it. This report describes the management of a 14-year-old boy with albinism. It highlights the possible link between albinism and HPS. It emphasises how important it is that dentists are aware of the medical problems associated with HPS.