多光谱图像
像素
压缩传感
探测器
荧光寿命成像显微镜
高光谱成像
显微镜
计算机科学
算法
材料科学
人工智能
物理
光学
荧光
作者
Alberto Ghezzi,Andrea Farina,Andrea Bassi,Gianluca Valentini,Ivan Labanca,Giulia Acconcia,Ivan Rech,Cosimo D'Andrea
出处
期刊:Optics Letters
[The Optical Society]
日期:2021-03-10
卷期号:46 (6): 1353-1353
被引量:14
摘要
Multispectral/hyperspectral fluorescence lifetime imaging microscopy ( λ FLIM) is a promising tool for studying functional and structural biological processes. The rich information content provided by a multidimensional dataset is often in contrast with the acquisition speed. In this work, we develop and experimentally demonstrate a wide-field λ FLIM setup, based on a novel time-resolved 18 × 1 single-photon avalanche diode array detector working in a single-pixel camera scheme, which parallelizes the spectral detection, reducing measurement time. The proposed system, which implements a single-pixel camera with a compressive sensing scheme, represents an optimal microscopy framework towards the design of λ FLIM setups.
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