Strain-release enabled [3 + 2] annulation of 3-aminooxetanes with simple CN bonds: facile synthesis of imidazolidines

An unprecedented [3+2] annulation of readily available 1,3,5-triazinanes and 3-aminooxetanes is accomplished for the first time, enabling the convenient synthesis of a range of structurally diverse 4-hydroxymethyl imidazolidines.