An analysis of preoperative risk factors in orthotopic liver transplantation

Objective To determine preoperative risk factors being related to early mortality after liver transplantation. Methods Clinical and laboratory data of 50 patients underwent liver transplantation were retrospectively analyzed. The relationship between the 20 possible preoperative risk factors and early mortality after orthotopic liver transplantation was investigated using logistic regression. Results Amongst the 20 possible risk factors, only cute physiology, age and chronic health evaluation (APACHE Ⅲ) scores, history of infection and preoperative serum creatinine level had a significant independent association with early mortality. The examination of the receiver operating characteristics (ROC) curve showed that the cutpoints of APACHE Ⅲ score and serum creatinine were 60 points and 140 μmol/L. Conclusions The outcome is poor if a patient has an existence of infection, APACHE Ⅲ score ≥60 and/or serum creatinine ≥140 μmol/L.