高尔基体
细胞生物学
毛囊
生物
甲状腺
小泡
基底膜
内质网
形态发生
化学
液泡
滤泡细胞
超微结构
解剖
内分泌学
膜
生物化学
细胞质
基因
出处
期刊:PubMed
日期:1979-01-01
卷期号:68 (1): 43-60
被引量:3
摘要
From the 20 mm stage, in the cells of the dogfish embryo thyroid, some Golgi vesicles get the ability to trap iodine. At subsequent stages, electrondense intracytoplasmic cavities with microvilli are observed in the Golgi field; their membranes also trap iodine. These cavities increase in volume, draw toward the cellular periphery and export their contents in an intercellular space previously limited by tight junctions. The same events occur in several adjacent cells, which constitute the first follicular lumen. The last stage of follicular individualization is basement membrane formation. Arguments are given which support the hypothesis of the Golgi origin of intracytoplasmic cavities with microvilli. Iodine organification just as thyroid hormones synthesis and secretion occur at 25 mm stage, when cells are not grouped in follicle. It is concluded that cells containing intracytoplasmic cavities with microvilli are fully functional units.
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