Risk factors analysis of adjacent and remote vertebral refracture after PKP

Objective To analyze the risk factors of adjacent and remote vertebral refracture after percutaneous kyphoplasty(PKP). Methods A total of 92 patients admitted in the Spine Center of the 306 th Hospital of PLA, who undergoing PKP due to osteoporotic vertebral compression fractures from January 2009 to June 2011 were retrospectively analyzed. According to the follow-up results,the patients were divided into fracture group and control group. The following clinical data were analyzed, including gender,age,bone mineral density T score,surgical vertebral body position(thoracic lumbar segment/non thoracic lumbar segment) and bone cement dosage,bone cement injection mode(single/double side),bone cement leakage,vertebral fracture number,vertebral surgery number,postoperative VAS score,long-term glucocorticoid use history and imageological data. Results Logistic regression analysis showed that lower BMD(OR=0.159) and the incidence of bone cement leakage(OR=6.502)were high risk factors of vertebral refracture(P0.05). Conclusion Severe osteoporosis and bone cement leakage are high risk factors of adjacent and remote vertebral refracture after PKP.