Advances in Cancer Research and Wnt5a

Wnt 5a is an important member of the Wnt family,played an important role in the process of tumor occurrence. Research shows that the role of Wnt 5a play in different tumors may be different,and the gene is highly expressed in some tumor cells,appear to have potential oncogene; while low Wnt 5a gene expression in some tumor cells,may play a tumor suppressor gene effect. Wnt 5a play a role in tumor cells may be associated with activation of Wnt /β- catenin signaling pathway or the classical non- classical Wnt /Ca2 +signaling pathway. As researchers study the deepening of Wnt 5a,making the gene gradually become the treatment of cancer and prognosis of valid targets. This article Wnt 5a Review of progress in cancer pathogenesis below.