甲氨蝶呤
皮疹
医学
坏死
中毒性表皮坏死松解
红斑
粘膜炎
皮肤病科
银屑病
白细胞减少症
不利影响
粘膜皮肤区
毒性
胃肠病学
外科
内科学
疾病
作者
Christopher J. Kennedy,John A. Thompson
标识
DOI：10.1080/15563650.2025.2532616
摘要
Methotrexate-induced epidermal necrosis is an uncommon, potentially fatal, adverse reaction to methotrexate. Early diagnosis of methotrexate-induced epidermal necrosis can prompt early intervention with calcium folinate and hopefully mitigate potentially fatal outcomes associated with methotrexate toxicity.
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