Fertility-preserving treatment for stage IA endometrial cancer: a systematic review and meta-analysis

The increasing use of fertility-preserving treatments in reproductive-aged patients with early-stage endometrial cancer necessitates robust evidence on the effectiveness of oral progestins and levonorgestrel-releasing intrauterine device (LNG-IUD). We conducted a systematic review and meta-analysis to examine outcomes following these two primary progestin-based therapies in reproductive-aged patients with early-stage endometrial cancer.