Unlocking the benefits of aerobic exercise for MAFLD: a comprehensive mechanistic analysis

Aerobic exercise alleviates MAFLD progression by orchestrating a complex regulatory network involving energy metabolism, stress response, post-transcriptional modification, and inter-organ crosstalk. This review clarifies the key molecular targets and signaling pathways underlying aerobic exercise's therapeutic effects, providing a theoretical basis for exploring potential targeted interventions and guiding future drug development for MAFLD.