炎症体
炎症
巨噬细胞极化
巨噬细胞
细胞生物学
癌症研究
化学
生物
免疫学
生物化学
体外
作者
M CHEN,Yu Chen,Rui Fu,SaiYue Liu,Haixia Li,T. Y. Shen
标识
DOI:10.1186/s12967-024-05314-4
摘要
Atox1 plays a pro-inflammatory role, promotes M1 polarization of macrophages, and increases the concentrations of pro-inflammatory cytokines in intestinal tissue by regulating the ROS-NLRP3 inflammasome pathway. Atox1 is a potential therapeutic target in IBD.
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