Nickel-Catalyzed Hydrocarboxylation of Styrenes with Carbon Dioxide and Water

The nickel-catalyzed hydrocarboxylation of styrenes with carbon dioxide, employing water as a formal hydride source, has been effectively established, yielding the α-aryl carboxylic acid with commendable regioselectivity and yield. Furthermore, the catalytic asymmetric hydrocarboxylation of styrenes has been established, albeit with limited enantioselectivity.