谷氨酸棒杆菌
肌醇
枯草芽孢杆菌
代谢工程
化学
蔗糖
生物化学
食品科学
生物技术
生物
细菌
酶
遗传学
受体
基因
作者
Ken-ichi Yoshida,Michael Bott
标识
DOI:10.1016/j.copbio.2024.103114
摘要
D-chiro-inositol and scyllo-inositol are known for their health-promoting properties and promising as ingredients for functional foods. Strains of Bacillus subtilis and Corynebacterium glutamicum were created by metabolic engineering capable of inexpensive production of these two rare inositols from myo-inositol, which is the most common inositol in nature. In addition, further modifications have enabled the synthesis of the two rare inositols from the much-cheaper carbon sources, glucose or sucrose.
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