Donor-Derived Cell-Free DNA in Biopsy-Proven Antibody-Mediated Rejection Versus Recurrent IgA Nephropathy After Kidney Transplantation

Recurrent primary disease causes graft loss in 8% of kidney transplant recipients.1 IgA nephropathy (IgAN) is one of the most prevalent recurrent primary diseases and is associated with impaired graft function and premature graft loss.2 Young recipient age,S1 rapid progression of native kidney disease, close human leukocyte antigen-matching,S2 and early steroid withdrawal3,S3 have been described as possible risk factors for recurrent IgAN.