医学
危险系数
优势比
置信区间
倾向得分匹配
内科学
淋巴细胞
心脏病学
主动脉夹层
外科
胃肠病学
中性粒细胞与淋巴细胞比率
主动脉
作者
Fan Yang,Jitao Liu,Lyufan Chen,Ruixin Fan,Hongke Zeng,Qingshan Geng,Jianfang Luo
出处
期刊:Angiology
[SAGE]
日期:2021-05-06
卷期号:72 (10): 953-960
被引量:8
标识
DOI:10.1177/00033197211012514
摘要
Lymphocyte-related blood parameters (LRBP), including neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio, and lymphocyte-monocyte ratio, could reflect a patient’s overall inflammatory status. We aimed to clarify the association between preoperative LRBP and outcomes of type B aortic dissection (TBAD) patients undergoing thoracic endovascular aortic repair (TEVAR). A total of 841 patients were enrolled from 2010 to 2017. Twenty-six (3.1%) patients died during hospitalization and 71 (8.7%) patients died after a median follow-up of 47.3 months. Multivariate analyses showed that the NLR was the only independent predictor for in-hospital death (odds ratio, 1.15; 95% confidence interval [CI], 1.09-1.22; P < .001); 4.1 was identified as the optimum threshold for NLR after applying the X-tile program. Propensity score matching (PSM) was performed to diminish bias and yielded 174 matched pairs. Neutrophil-lymphocyte ratio >4.1 was demonstrated to be independently associated with follow-up mortality before (hazard ratio [HR], 2.53; 95% CI, 1.44-4.43; P = .001) and after PSM (HR, 3.11; 95% CI, 1.35-7.15; P = .008). The relationship between LRBP and follow-up reintervention or stroke were not significant ( P > .05 for both). Elevated NLR was an independent indicator for in-hospital and follow-up mortality in patients with TBAD undergoing TEVAR; this might provide additional risk stratification.
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