表观基因组
乙酰化
组蛋白
表观遗传学
转录组
饮酒量
神经科学
生物
酒
DNA甲基化
细胞生物学
化学
基因
遗传学
基因表达
生物化学
作者
Irene de Diego,Annika Müller-Eigner,Shahaf Peleg
标识
DOI:10.1016/j.tibs.2019.11.002
摘要
Recent studies demonstrated that alcohol consumption can induce epigenetic changes in the brain, although the exact mechanism underlying such changes remained unclear. Now, a report by Mews et al. shows a direct link between alcohol consumption and histone acetylation changes in the brain, which are mediated by the neuronal acetyl-CoA synthase, ACSS2. Recent studies demonstrated that alcohol consumption can induce epigenetic changes in the brain, although the exact mechanism underlying such changes remained unclear. Now, a report by Mews et al. shows a direct link between alcohol consumption and histone acetylation changes in the brain, which are mediated by the neuronal acetyl-CoA synthase, ACSS2.
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