Facile Synthesis of Silver Nanoparticles with High Antibacterial Activity

We report on a reverse microemulsion method for the synthesis of silver nanocrystals and examine their antibacterial activities. As the molar ratio of water to sodium bis(2-ethylhexyl) sulfosuccinate (AOT) increases to 25, a morphology transition from a sphere-like nanocrystal to a wire-like one was observed. For both the gram-negative and gram-positive bacteria, the wire-like silver nanocrystal showed higher antibacterial activities. We conclude that the morphology of silver nanocrystals dominates their antibacterial activity.