萜类
化学
细胞毒性
免疫印迹
立体化学
药理学
二维核磁共振波谱
细胞培养
生物测定
体外
生物碱
肿瘤细胞
胶质瘤
生物化学
细胞
生物活性
结构-活动关系
三萜类
光谱分析
萜烯
效力
作者
Leyi Fu,Zhiling Yao,Jiming Chen,Zitian Peng,Liju Zhang,Zhe Ren,Tao Liu,Yifei Wang
标识
DOI:10.1002/cbdv.202503722
摘要
= 5.6 µM) and potently abrogated cell migration and invasion in a dose-proportional manner by suppressing PI3K/AKT/mTOR phosphorylation, as confirmed by Transwell and Western blot analyses. Bioinformatics analysis further suggested EGFR as a potential upstream target mediating these effects. These findings indicated A. argyi as a possible source of bioactive terpenoids with anti-glioma potential, providing a theoretical basis for further pharmacological studies.
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