非酒精性脂肪肝
非酒精性脂肪性肝炎
脂肪肝
胃肠病学
内科学
医学
疾病
作者
Mercedes Vázquez–Chantada,Aintzane González-Lahera,Ibon Martínez‐Arranz,Carmelo García‐Monzón,Manuela M. Regueiro,Juan L. García‐Rodríguez,Karin Schlangen,Iñaki Mendibil,Naiara Rodríguez‐Ezpeleta,Juan José Lozano,Karina Banasik,Johanne Marie Justesen,Torben Joergensen,Daniel R. Witte,Torsten Lauritzen,Torben Hansen,Oluf Pedersen,Nicolas Veyrie,Karine Clément,Joan Tordjman
出处
期刊：Hepatology
[Lippincott Williams & Wilkins]
日期：2012-09-07
卷期号：57 (2): 505-514
被引量：38
摘要
Genetic variants of SLC2A1 are associated with NAFLD, and in vitro down-regulation of this gene promotes lipid accumulation. Moreover, the oxidative response detected in siSLC2A1-THLE2 cells corroborated the antioxidant properties previously related to this gene and linked the most representative clinical characteristics of NAFLD patients: oxidative injury and increased lipid storage.
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