癌症研究
免疫系统
卵巢癌
医学
肿瘤科
癌症
内科学
免疫学
作者
Lin Cheng,Shichao Zhou,Shaoqing Zhou,Kaixuan Shi,Yan Cheng,Mei‐Chun Cai,Kaiyan Ye,Lifeng Lin,Zhenfeng Zhang,Chenqiang Jia,Huaijiang Xiang,Jingyu Zang,Meiying Zhang,Xia Yin,Ying Li,Wen Di,Guanglei Zhuang,Li Tan
出处
期刊：Cancer Research
[American Association for Cancer Research]
日期：2022-07-20
卷期号：82 (19): 3588-3602
被引量：52
标识
DOI：10.1158/0008-5472.can-22-0222
摘要
This study dissects the specific roles of CDK12 and CDK13 in ovarian cancer and develops a CDK12/CDK13 inhibitor that impairs both tumor and immune cells, which could guide future CDK12 inhibitor development.
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