医学
曲妥珠单抗
单克隆抗体
单克隆
食品药品监督管理局
肿瘤科
药品
机制(生物学)
表皮生长因子受体
作用机理
人表皮生长因子受体2
药理学
抗体
内科学
癌症
免疫学
乳腺癌
体外
化学
认识论
哲学
生物化学
摘要
Overexpression of human epidermal growth factor receptor type 2 (HER2) in breast cancer is associated with decreased overall survival. Trastuzumab, a humanized monoclonal antibody that targets HER2, is approved by the Food and Drug Administration for patients with invasive breast cancers that overexpress HER2. This review considers the mechanism of action and the use of this agent.
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