医学
皮肤癌
重症监护医学
恶性肿瘤
癌症
疾病
治疗方式
模式
免疫疗法
人口
流行病学
转化研究
治疗方式
皮肤病科
病理
外科
内科学
环境卫生
社会学
社会科学
作者
Mário Amaral Simões,João Sousa,Alberto A. C. C. Pais
出处
期刊:Cancer Letters
[Elsevier]
日期:2015-02-01
卷期号:357 (1): 8-42
被引量:278
标识
DOI:10.1016/j.canlet.2014.11.001
摘要
Skin cancers are by far the most common malignancy of humans, particularly in the white population. The growing incidence of cutaneous malignancies has heralded the need for multiple treatment options. Although surgical modalities remain the mainstay of treatment, new research and fresh innovation are still required to reduce morbidity and mortality. Approaches for skin cancer may pass through new technological methods instead of new molecules. The first part of this paper provides a review of the state of the art regarding skin cancer disease as well as epidemiology data. Then, it describes the gold standards of the current recommended therapies worldwide and the actual needs of these patients. This is the first paper that highlights the novel and future therapeutic perspectives for the treatment of skin malignancies, new therapeutic agents and promising technological approaches, from nanotechnology to immunotherapy.
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