Analysis of neoadjuvant chemotherapy efficacy in TACE of liver metastasis of colorectal cancer

Objective To assess the therapeutic efficacy of comprehensive management and pre-operative chemotherapy of liver metastasis of colorectal cancer. Methods Two weeks before and after the neoadjuvant chemotheray. Its therapeutic efficacy was assessed by: 1) BUS or CT,2)TACE,3) BUS after TACE,4)Resection,5)6 courses of SVC,6)BUS or CT. Results BUS displayed that PSV was 0. 87m/s and RI 0. 83 in internal artery of tumor. After TACE for 1 week, PSV was 0. 63m/s and RI 0. 85 (P<0. 05). Pathological examination showed that the regional necrosis and lymphoma repose were significantly different. All the patients undergoing the TACE were alive without tumors and the 1-year survival rate was 92. 9%. Conclusion The neoadjuvant chemotherapy by TACE can decrease blood supply and increases necrosis for tumors. Key words: Colorectal-neoplasms; Liver-metastasis; TACE; Neoadjuvant chemotherapy