This research focuses on route optimization for autonomous ground vehicles, with key applications in precision agriculture, logistics and surveillance. Its goal is to create planning techniques that increase productivity and flexibility in changing settings. To achieve this, a PRISMA-based systematic literature review was carried out, encompassing works published during the last five years in databases like IEEE Xplore, ScienceDirect and Scopus. The search focused on topics related to route optimization, unmanned ground vehicles and heuristic algorithms. From the analysis of 56 selected articles, trends, technologies and challenges in real-time route planning were identified. Fifty-seven percent of the recent studies focus on UGV optimization, with prominent applications in agriculture, aiming to maximize efficiency and reduce costs. Heuristic algorithms, such as Humpback Whale Optimization, Firefly Search and Particle Swarm Optimization, are commonly employed to solve complex search problems. The findings underscore the need for more flexible planning techniques that integrate spatiotemporal and curvature constraints, allowing systems to respond effectively to unforeseen changes. By increasing their effectiveness and adaptability in practical situations, our research helps to provide more reliable autonomous navigation solutions for crucial applications.