Ru-based nanoparticle catalyzed direct H/D exchange of silanes

Deuterated silanes, among the most important reagents for introducing deuterium atoms, are widely utilized in organic synthesis. However, synthesizing versatile deuterated silanes under mild conditions remains a challenge. In this study, we report an effective method for H/D exchange of silanes using Ru-bpy@γ-Al₂O₃. Deuterium gas (D₂), generated in situ from the electrolysis of D₂O, served as the deuterium source. Various hydrosilanes and hydrosiloxanes undergo smooth H/D exchange under mild conditions. Furthermore, the products were applied for the derivatization of a wide range of compounds.