氧化应激
蛋白激酶B
细胞生物学
PI3K/AKT/mTOR通路
化学
生物
信号转导
生物化学
作者
Alan Tang,Nicholas Anthony Besley,Rose Trimpey-Warfhatig,Ping Yang,Howard Wessel,L. R. Brown,Ziv Z. Kirshner,Glenn J. Jaffe
标识
DOI:10.1016/j.exer.2024.110060
摘要
Oxidative stress-mediated retinal pigment epithelial (RPE) cell damage is associated with age-related macular degeneration (AMD). ST266 is the biological secretome produced by a novel population of amnion-derived multipotent progenitor cells. Herein, we investigated the effect of ST266 on RPE cell injury induced by hydroquinone (HQ), a cigarette smoke related oxidant, hydrogen peroxide (H
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