Which Strategy for Deciding Statin Treatment in Primary-Prevention Patients? A Three-Way Comparison

To compare the strengths of three approaches for deciding which primary-prevention patients should be treated with a statin, investigators analyzed data from the Copenhagen General Population Study on 37,892 subjects enrolled in 2003–2008 and free of atherosclerotic cardiovascular disease (ASCVD), diabetes, and statin use at baseline (age range, 40–75; mean age, 56; 57% women). The three approaches to determine eligibility for a primary-prevention statin were: