虎耳草毒素
检出限
生物传感器
石墨烯
电位滴定法
选择性
电极
色谱法
再现性
线性范围
化学
材料科学
纳米技术
毒素
有机化学
生物化学
物理化学
催化作用
作者
Spyridoula Bratakou,Georgia‐Paraskevi Nikoleli,Christina G. Siontorou,Dimitrios P. Nikolelis,Stephanos Karapetis,Nikolaos Tzamtzis
标识
DOI:10.1002/elan.201600652
摘要
Abstract A miniaturized potentiometric saxitoxin sensor on graphene nanosheets with incorporated lipid films and Anti‐STX, the natural saxitoxin receptor, immobilized on the stabilized lipid films is described in the present paper. An adequate selectivity for detection over a wide range of toxin concentrations, fast response time of ca. 5–20 min, and detection limit of 1 nM have been achieved. The proposed sensor is easy to construct and exhibits good reproducibility, reusability, selectivity, long shelf life and high sensitivity of ca. 60 mV/decade of toxin concentration. The method was implemented and evaluated in lake water and shellfish samples. This novel ultrathin film technology is currently adapted to the rapid detection of other toxins that could be used in bioterrorism.
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