Objective Automatic Assessment of Rehabilitative Speech Treatment in Parkinson's Disease

康复 发声 帕金森病 会话(web分析) 物理医学与康复 听力学 元音 心理学 语音识别 计算机科学 医学 疾病 物理疗法 病理 万维网
作者
Athanasios Tsanas,Max A. Little,Cynthia Fox,Lorraine O. Ramig
出处
期刊:IEEE Transactions on Neural Systems and Rehabilitation Engineering [Institute of Electrical and Electronics Engineers]
卷期号:22 (1): 181-190 被引量:209
标识
DOI:10.1109/tnsre.2013.2293575
摘要

Vocal performance degradation is a common symptom for the vast majority of Parkinson's disease (PD) subjects, who typically follow personalized one-to-one periodic rehabilitation meetings with speech experts over a long-term period. Recently, a novel computer program called Lee Silverman voice treatment (LSVT) Companion was developed to allow PD subjects to independently progress through a rehabilitative treatment session. This study is part of the assessment of the LSVT Companion, aiming to investigate the potential of using sustained vowel phonations towards objectively and automatically replicating the speech experts' assessments of PD subjects' voices as "acceptable" (a clinician would allow persisting during in-person rehabilitation treatment) or "unacceptable" (a clinician would not allow persisting during in-person rehabilitation treatment). We characterize each of the 156 sustained vowel /a/ phonations with 309 dysphonia measures, select a parsimonious subset using a robust feature selection algorithm, and automatically distinguish the two cohorts (acceptable versus unacceptable) with about 90% overall accuracy. Moreover, we illustrate the potential of the proposed methodology as a probabilistic decision support tool to speech experts to assess a phonation as "acceptable" or "unacceptable." We envisage the findings of this study being a first step towards improving the effectiveness of an automated rehabilitative speech assessment tool.
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