Organic Iodide Aided Carbonylation of Terminal Acetylenes with Palladium Catalyst

Abstract Carbonylation of various terminal acetylenes in the presence of a catalytic amount of organic iodides or amine•HI salt and palladium complexes was found to produce 2-substituted acrylamides in good yields under mild conditions (5 atm, 120 °C, 6 h).