Effects of Three Kinds of Cyclodextrin Derivates on Solubilization and Stability under UV Irradiation of Resveratrol

The effects of three kinds of cyclodextrin derivates such as β-cyclodextrin,hydroxypropyl-β-cyclodextrin(HP-β-CD) and 2,6-di-O-methyl-β-cyclodextrin on solubilization and stability of resveratrol were investigated by means of UV spectroscopy,phase-solubility and 1H NMR. The results showed that resveratrol could form an inclusion compound(1:1)with the three cyclodextrin derivates. The solubilization effect of HP-β-CD was the best among them. The stability of resveratrol under UV irradiation could be improved to a certain extent by HP-β-CD but reduced by others.