Microstructures of Learning: Novel methods and approaches for assessing structural and functional changes underlying knowledge acquisition in the brain

Multidimensional diffusion MRI is a promising new MRI approach that has the potential to non-invasively give information about brain microstructure at an unprecedented level of detail. The present contribution briefly reviews the salient features of the novel method, its historical background and differences with conventional methods, as well as the remaining challenges that have to be overcome in order to make it applicable in learning studies.