A Clinical Study on the Effect of Mosapride on Functional Dyspepsia

Objective To investigate the clinical effect of mosapride in treating functional dyspepsia(FD).Methods Eighty-four patients meeting Rome Ⅱcriterion were randomly received either mosapride 5mg tid(group,A 42 patients)or domperidone 5mg tid(group,B 42 patients) for 4 weeks.The symptoms were evaluated before treatment and at the end of 4th week.Gastric emptying of solid food was examined by using radiopaque markers in twelve patitens from group A and group B,respectively.Results The clinical curative rates were 85.71% in group A and 66.67% in group B.There was significant difference between two groups(P0.05).After the treatment the average number of barium strip expelled from stomach were 4 in group A and 3 in group B before treatment and was significantly increased to 18 and 12(P0.01),respectively.Conclusion Mosapride has better clinical effect than domperidone on the treatment of FD.