化学
皮诺森布林
分子内力
键离解能
咖啡酸
标准生成焓
热化学
氢键
对香豆酸
键能
药物化学
计算化学
物理化学
离解(化学)
立体化学
有机化学
分子
类黄酮
抗氧化剂
阿魏酸
食品科学
作者
Elena Alvareda,Pablo A. Denis,Federico Iribarne,Margot Paulino
标识
DOI:10.1016/j.comptc.2016.06.021
摘要
By means of G4 theory and M06-2X calculations we investigated the thermochemistry and C–OH bond ruptures of quercetin, fistein, lutelin, caffeic acid, pinocembrin and p-coumaric acid. Notwithstanding the fact that we observed a good agreement for the prediction of the weakest O–H bond, the mean absolute deviation (MAD) between the bond dissociation energies (BDE) computed at the G4 and M06-2X/6-311+G(3df,2p) levels was 5.0 kcal/mol. With regard to the ΔHof,0 computed at the M06-2X/6-311+G(3df,2p) level, the MAD was 10.0 kcal/mol. Therefore, thanks to error cancellation the error found for the O–H BDE was smaller. Intramolecular hydrogen bond is one of the key factors stabilizing the oxygen radicals formed when the CO–H bonds are broken. Finally, we propose the following enthalpies of formation at 0 K: −222.0, −174.5, −180.2, −134.4, −109.7 and −91.9 kcal/mol for quercetin, fistein, lutelin, caffeic acid, pinocembrin and p-coumaric acid, respectively.
科研通智能强力驱动
Strongly Powered by AbleSci AI