Objective To probe the relationship between the cholelithiasis and clonorchiasis diagnosed by ultrasonography.Methods Analized respectively the morbidities of the cholelithiasis and clonorchiasis diagnosed by ultrasonography of 1326 objectives who live in the clonorchiasis-prevalent area.Results The total morbidity of the clonorchiasis was about 51.4%,while the total morbidity of the cholelithiasis was about 30.0%,the morbidity of male persons was higher obviously than female ones(P0.01).The morbidity of cholelithiasis among the clonorchiasis patients was 51.6%,while the morbidity of cholelithiasis among non-clonorchiasis objectives was about 12.1%,there was significant difference statistically between them(P0.01).Conclusion The clonorchiasis is a dangerous factor for the cholelithiasis in the clonorchiasis-prevalent area.