An Efficient Approach to the Synthesis of 5-Aryl-1H-tetrazole Derivatives Accompanying with the Cleavage of Ester Group

5-Phenyl-1H-tetrazoles were synthesized by catalytic [3＋2] cycloaddition with aryl nitriles and sodium azide.Indium trichloride was used as an efficient catalyst.The tetrazoles binding with varieties of functional groups were synthesized in good to quantitative yields.This tetrazole synthetic protocol also showed remarkable de-carboxylation activity.Esters were cleaved to carboxylic acids or alcohols in one pot.