医学
组织发生
病理
间充质干细胞
间质细胞
软组织
病变
肺
结节性筋膜炎
免疫组织化学
内科学
作者
Venkateswar R. Surabhi,Steven S. Chua,Rajan Patel,Naoki Takahashi,Neeraj Lalwani,Srinivasa R. Prasad
标识
DOI:10.1016/j.rcl.2015.12.005
摘要
Inflammatory myofibroblastic tumor (IMT) is a mesenchymal neoplasm of intermediate biological potential with a predilection for the lung and abdominopelvic region. IMT represents the neoplastic subset of the family of inflammatory pseudotumors, an umbrella term for spindle cell proliferations of uncertain histogenesis with a variable inflammatory component. IMTs show characteristic fasciitis-like, compact spindle cell and hypocellular fibrous histologic patterns and distinctive molecular features. Imaging findings reflect pathologic features and vary from an ill-defined, infiltrating lesion to a wellcircumscribed, soft tissue mass owing to variable inflammatory, stromal, and myofibroblastic components.
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