Dihydroquinazolinones as Photocatalyst-Free Carbamoyl Radical Precursors for Ynamide Formation

A photocatalyst-free, visible-light-enabled alkynylation of carbamoyl radicals has been developed, facilitating streamlined access to alkynyl amides (ynamides). We use readily prepared carbamoyl-functionalized dihydroquinazolinone precursors, which undergo aromatization-driven C-C bond cleavage...