角质层
皮肤干燥
化学
表皮(动物学)
脱水
人体皮肤
皮肤屏障
作者
Suzy Cointereau-Chardon,Elisa Caberlotto,Marco Vicic,Frederic Flament
摘要
Objective To evaluate the reliability of data self-recorded by subjects enrolled in a study for skin surface hydration and Trans-Epidermal Water Loss (TEWL). Methods A connected device, previously described, simultaneously records both the hydration status and the TEWL on the same skin site. The effects of a Xanthane-based gel containing low concentrations of glycerol (3% or 7%) applied on both face and forearms of Caucasian women, were self-recorded at various times for 24 hours, outside of Research facility. Results In the first-hour post application, the skin hydration and TEWL values show a sharp increase and decrease, respectively. They progressively recover their initial values 24 hours post washing, on both skin sites. A significant dose effect of glycerol (ie, 3% vs 7%) was obtained on both skin sites. The repeatability of data was found acceptable in both parameters, although more precise on arms than face, probably linked to an easier handling of the device. Conclusion The use of this skin measuring connected device outside of Research facility, following a training of subjects, leads to reliable data. Such approach could be extended to other connected devices.
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