Study for Cases of Recurrenc After Endoscopic Resection in Early Gastric Cancer

Introduction: Endoscopic resection (ER) is widely accepted treatment for early gastric cancer (EGC), but little is known about recurrence after ER. Methods: The aim of this study is to investigate cases of recurrence after ER for EGC. We performed a retrospective review of medical records of 126 patients with EGC underwent ER. Results: The median follow up period was 26.7 months. During a follow up, a total of 10 patients (7.94%) developed recurrence in enrolled patients. According to univariate logistic regression analysis, piecemeal resection (odds ratio [OR] 7.067, 95% confidence interval [CI] 1.706-29.285, P=0.007) and tumorpositive resection margin (OR 33.292, 95% CI 7.064-159.904, P < 0.0001) were significant risk factors for cancer recurrence after ER. However, there was no significant factor for recurrence in multivariate logistic regression analysis. Conclusion: This study showed that piecemeal resection and tumor-positive resection margin were probable risk factors for recurrence after ER for EGC. Therefore, a study in a large number of patients and a longer period might show that piecemeal resection and tumor-positive resection margin are risk factors for recurrence.Figure 1Figure 2