免疫吸附
医学
视神经脊髓炎
甲基强的松龙
多发性硬化
光谱紊乱
麻醉
不利影响
内科学
免疫学
抗体
精神科
作者
Rui Li,Jingqi Wang,Cong Liu,Xiangfu Liu,Muyang Chu,Yanyu Chang,Yuge Wang,Xia Wang,Boguang Yu,Ling Li,Hui Yang,Huan Yang,Xueqiang Hu,Wei Qiu
标识
DOI:10.1016/j.jneuroim.2021.577604
摘要
We aimed to evaluate the value of immunoadsorption (IA) treatment after the failure of intravenous methylprednisolone (IVMP) therapy for neuromyelitis optica spectrum disorder (NMOSD). Sixty-one NMOSD attacks unresponsive to IVMP were included: 22 patients received rescue IA (IVMP+IA), 24 underwent rescue plasma exchange (PE) (IVMP+PE), and 21 received no further rescue therapy (IVMP alone). The improvement frequencies were higher in the IVMP+IA and IVMP+PE groups than in the IVMP-alone group (P = 0.024). The effective period for IA treatment may be longer than previously thought. IA treatment for IVMP-resistant NMOSD attacks was effective and comparable to PE treatment.
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