P2‐018: The Effect of a Computer‐Based Cognitive Training Program on Cognition

Effective non-pharmacological cognitive interventions to prevent Alzheimer’s dementia or slow its progression are an urgent international priority. The effect of computer-based cognitive training has not been demonstrated yet. The purpose of this study is to know whether the computer-based cognitive training improved cognitive abilities in patients with mild cognitive disorder and early stage of dementia. Totally 40 participants (24 with MCI and 16 with mild Alzhiemer dementia) participated in this study. To test the effectiveness of computer-based cognitive training programs to cognition, all patient were randomly allocated to an intervention group (n=20) or a control group (n=20). The intervention group received regularly computer-based cognitive training totally 20 times for 10 weeks. Neuropsychological examinations were conducted before and after this period. After 10 weeks, intervention group showed a significant change in language of K-MMSE compared with baseline cognitive examinations. Also, there was greater improvement in attention (backward digit span), calculation, memory, and frontal function for the intervention group as compared with controls. Patients with mild cognitive disorder showed marked improvements in language and visuospatial capacity, while patients with dementia showed no or slight improvement in these fields. Computer-based cognitive training might have beneficial effect on general cognitive function in both mild cognitive disorder and dementia. However, conspicuous effectiveness showed only in mild cognitive disorder.