Topical Delivery of Curcuma longa Extract Loaded Nanosized Ethosomes to Combat Facial Wrinkles Research Article

Topical Delivery of Curcuma longa Extract Loaded Nanosized Ethosomes to Combat Facial Wrinkles The most important limitation in the management of facial wrinkles, includes the inability of antiwrinkle agent to penetrate into the deeper layers of the skin. In the present study, potential of ethosomes to deliver the antiwrinkle agent, “curcumin” into the deeper layers of skin has been investigated. Curcumin, obtained from rhizomes of Curcuma longa has well established antioxidant property which support its use as an antiwrinkle agent. Curcuma longa extract loaded ethosomes were prepared by hot method, and incorporated into cream.